醫師學術論文
Paper賴威達 Ted Weita Lai 副主任
血腦屏障保護著大腦免於腦水腫以及血中毒物的入侵,卻也阻礙藥物治療腦癌、神經退化疾病、以及精神疾病。賴威達研究員主要的研究專注於血腦屏障的發育、生理功能、病變、以及利用藥物控制血腦屏障通透性的方法。期望在未來,可以透過調控血腦屏障得以促進大腦的發育及生理功能、抑制大腦病變、以及幫助藥物傳輸至大腦以達到最佳治療效果。
相關連結
學術機構典藏
論文
期刊論文
期刊論文/Journal Paper (作者群,論文題目,期刊名稱,出版年月,卷號(期別):頁次起迄) |
日期 | |
1 | 王禹翔(WANG YU HSIANG)、陳思翰(CHEN SZU-HAN)、吳孟芷(Meng-Chih Wu)、楊雅嵐、王惠勵、劉哲維(Che-Wei Liu)、賴威達(Ted Weita Lai)*,Microglia through MFG-E8 signaling decrease the density of degenerating neurons and protect the brain from the development of cortical infarction after stroke,PLoS One,2024 Aug,19(8):e0308464-e0308464 | 2024 . 08 |
2 | 吳孟芷(Meng-Chih Wu)、王禹翔(WANG YU HSIANG)、賴威達(Ted Weita Lai)*,TAT peptide at treatment-level concentrations crossed brain endothelial cell monolayer independent of receptor-mediated endocytosis or peptide-inflicted barrier disruption,PLoS One,2023 Oct,18(10):e0292681 | 2023 . 10 |
3 | 楊雅嵐(Ya Lan Yang)、賴威達(Ted Weita Lai)*,Chronic Visual Stimulation with LED Light Flickering at 24, 40, or 80 Hz Failed to Reduce Amyloid β Load in the 5XFAD Alzheimer's Disease Mouse Model,eNeuro,2023 Aug,10(8): | 2023 . 08 |
4 | (Che-Wei Liu)、王禹翔(WANG YU HSIANG)、(Hwai-Lee Wang)、廖秀蓉(Kate Hsiurong Liao)、(Hsiao-Yun Chen)、(Hank Szuhan Chen)、賴威達(Ted Weita Lai)*,Blood–Brain Barrier Disruption in Preclinical Mouse Models of Stroke Can Be an Experimental Artifact Caused by Craniectomy,eNeuro,2022 Oct,9(5):0343-22 | 2022 . 10 |
5 | 王禹翔(WANG YU HSIANG)、賴威達(Ted Weita Lai)*,Drug-induced hyperglycemia as a potential contributor to translational failure of uncompetitive NMDA receptor antagonists,eNeuro,2021 Dec,8(6):0346-21 | 2021 . 12 |
6 | 劉哲維(Che-Wei Liu)、廖秀蓉(Kate Hsiurong Liao)、吳淨眉(Ching Mei Wu)、陳筱筠(Hsiao-Yun Chen)、王禹翔(WANG YU HSIANG)、賴威達(Wei-Ta Lai)*,Stroke injury induced by distal middle cerebral artery occlusion is resistant to N-methyl-D-aspartate receptor antagonism in FVB/NJ mice,NEUROREPORT,2021 Sep,32(13):1122-1127 | 2021 . 09 |
7 | Meng-Chih Wu(吳孟芷)、徐婕琳(Hsu, Jye-Lin)*、賴威達(Wei-Ta Lai)*,Evans blue dye as an indicator of albumin permeability across a brain endothelial cell monolayer in vitro,NEUROREPORT,2021 Aug,32(11):957-964 | 2021 . 08 |
8 | 吳淨眉(Ching Mei Wu)、賴威達(Wei-Ta Lai)*,Microglia depletion by PLX3397 has no effect on cocaine-induced behavioral sensitization in male mice,BRAIN RESEARCH,2021 Jun,1761():147391 | 2021 . 06 |
9 | 楊雅嵐(Ya Lan Yang)、賴威達(Wei-Ta Lai)*,Citric Acid in Drug Formulations Causes Pain by Potentiating Acid-Sensing Ion Channel 1,JOURNAL OF NEUROSCIENCE,2021 May,42(21):4596-4606 | 2021 . 05 |
10 | 楊雅嵐(Ya Lan Yang)、賴威達(Wei-Ta Lai)*,Native expression of ASIC1a and ASIC1b human homologues in the HEK 293 cell line allows pharmacological evaluation of analgesics targeting acid sensation in humans,NEUROREPORT,2020 Aug,31(12):865-870 | 2020 . 08 |
11 | 劉哲維(Che-Wei Liu)、廖秀蓉(Kate Hsiurong Liao)、曾欣(Hsin Tseng)、吳淨眉(Ching Mei Wu)、陳筱筠(Hsiao-Yun Chen)、賴威達(Wei-Ta Lai)*,Hypothermia but not NMDA receptor antagonism protects against stroke induced by distal middle cerebral arterial occlusion in mice,PLoS One,2020 Mar,15(3):e0229499 | 2020 . 03 |
12 | 潘健成(Kin-Shing Poon)、潘玉翎(Yu-Ling Pan)、廖秀蓉(Kate Hsiurong Liao)、王惠勵(Hwai-Lee Wang)、陳坤堡(Kuen-Bao Chen)、陳筱筠(Hsiao-Yun Chen)、劉玉成(Yu-Cheng Liu)、賴威達(Wei-Ta Lai)*,Isoflurane attenuates carbogen-induced blood–brain barrier disruption independent of body temperature in mice and rats,NEUROREPORT,2020 Jan,31(2):118-124 | 2020 . 01 |
13 | 廖秀蓉(Hsiu-Rong Liao)、魏嘉莉(Vivi Chiali Wei)、王惠勵(Hwai-Lee Wang)、陳筱筠(Hsaio-Yun Chen)、賴威達(Wei-Ta Lai)*,Carbogen inhalation opens the blood-brain barrier in rats without causing long-term metabolic or neurological deficit,BRAIN RESEARCH,2019 Oct,1720():146320-146320 | 2019 . 10 |
14 | 王惠勵(Hwai-Lee Wang)、郭玉華(Eva Yuhua Kuo)、賴威達(Lai, Ted Weita)*,Vascular delivery of intraperitoneal Evans blue dye into the blood-brain barrier-intact and disrupted rat brains,NEUROREPORT,2018 Aug,29(11): | 2018 . 08 |
15 | 劉玉成(Yu-Cheng Liu)、李昱達(Yu-Da Lee)、王惠勵(Hwai-Lee Wang)、廖秀蓉(Kate Hsiurong Liao)、陳坤堡(Kuen-Bao Chen)、潘健成(Kin-Shing Poon)、潘玉翎(Yu-Ling Pan)、賴威達(Ted Weita Lai)*,Anesthesia-Induced Hypothermia Attenuates Early-Phase Blood-Brain Barrier Disruption but Not Infarct Volume following Cerebral Ischemia,PLoS One,2017 Jan,12(1):e0170682 | 2017 . 01 |
16 | 鄭智忠(Chih-Chung Cheng)、楊雅嵐(Ya Lan Yang)、廖秀蓉(Kate Hsiurong Liao)、賴威達(Ted Weita Lai)*,Adenosine receptor agonist NECA increases cerebral extravasation of fluorescein and low molecular weight dextran independent of blood-brain barrier modulation,Scientific Reports,2016 Mar,6():23882-23882 | 2016 . 03 |
17 | 王惠勵(Hwai-Lee Wang)、賴威達(Ted Weita Lai)*,Optimization of Evans blue quantitation in limited rat tissue samples,Scientific Reports,2014 Oct,4(6588): | 2014 . 10 |
18 | 賴威達(Ted Weita Lai)*、(Shu Zhang)、王玉田(Yu-Tian Wang)*,Excitotoxicity and stroke: Identifying novel targets for neuroprotection,PROGRESS IN NEUROBIOLOGY,2014 Apr,115():157-188 | 2014 . 04 |
19 | 顏鳳慧(Lola Fenghuei Yen)、魏嘉莉(Vivi Chiali Wei)、郭玉華(Eva Yuhua Kuo)、賴威達(Ted Weita Lai)*,Distinct patterns of cerebral extravasation by Evans blue and sodium fluorescein in rats,PLoS One,2013 Jul,8(7):e68595-368595 | 2013 . 07 |
20 | 陳坤堡(Kuen-Bao Chen)、魏嘉莉(Vivi Chiali Wei)、顏鳳慧(Lola Fenghuei Yen)、潘健成(Kin-Shing Poon)、劉玉成(Yu-Cheng Liu)、鄭嘉遜(Ka-Shun Cheng)、張家昇(Chia-Sheng Chang)、賴威達(Ted Weita Lai)*,Intravenous mannitol does not increase blood brain barrier permeability to inert dyes in the adult rat forebrain,NEUROREPORT,2013 Apr,24(6):303-307 | 2013 . 04 |
21 | 陳坤堡(Kuen-Bao Chen)、郭玉華(Eva Yuhua Kuo)、潘健成(Kin-Shing Poon)、鄭嘉遜(Ka-Shun Cheng)、張家昇(Chia-Sheng Chang)、劉玉成(Yu-Cheng Liu)、賴威達(Ted Weita Lai)*,Increase in Evans blue dye extravasation into the brain in the late developmental stage,NEUROREPORT,2012 Aug,23(12):699-701 | 2012 . 08 |
22 | 賴威達(Ted Weita Lai)、徐偉成(Woei-Cherng Shyu)、王玉田(Yu-Tian Wang)*,Stroke intervention pathways: NMDA receptors and beyond,TRENDS IN MOLECULAR MEDICINE,2011 May,17(5):266-275 | 2011 . 05 |
23 | 賴威達(Ted Weita Lai)、王玉田(Yu-Tian Wang)*,Fashioning drugs for stroke,NATURE MEDICINE,2010 Dec,16(12):1376-1378 | 2010 . 12 |
24 | (Changiz Taghibiglou)、(Henry G S Martin)、賴威達(Ted Weita Lai)、(Taesup Cho)、(Shiv Prasad)、(Luba Kojic)、(Jie Lu)、(Yitao Liu)、(Edmund Lo)、(Shu Zhang)、(Julia Z Z Wu)、(Yu Ping Li)、(Yan Hua Wen)、(Joon-Hyuk Imm)、(Max S Cynader)、王玉田(Yu-Tian Wang)*,Role of NMDA receptor–dependent activation of SREBP1 in excitotoxic and ischemic neuronal injuries,NATURE MEDICINE,2009 Dec,15(12):1399-1406 | 2009 . 12 |
25 | (Yitao Liu)、(Tak Pan Wong)、(Michelle Aarts)、(Amanda Rooyakkers)、(Lidong Liu)、賴威達(Ted Weita Lai)、吳東川(Dong-Chuan Wu)、(Jie Lu)、(Michael Tymianski)、(Ann Marie Craig)、王玉田(Yu-Tian Wang)*,NMDA Receptor Subunits Have Differential Roles in Mediating Excitotoxic Neuronal Death Both In Vitro and In Vivo,JOURNAL OF NEUROSCIENCE,2007 Mar,27(11):2846-2857 | 2007 . 03 |
研討會論文
研討會論文/Conference Papers (發表主題或論文名稱,研討會名稱,演講地點,研討會期間,受邀演講題目) |
日期 | |
1 | Microglial phagocytosis of neurons protects brain during ischemic stroke,SfN 2023,Washington DC,2023.11.11~2023.11.15, | 2023 . 11 |
2 | ,第四屆生物科技寒令營,中國醫藥大學,2019.01.24~2019.01.26,神經科學與生物科技的連結 | 2019 . 01 |
3 | ,The 2nd CMU-MU Joint Symposium,B2, Evergreen Laurel Hotel, Taichung,2019.01.02~2019.01.04,Manipulation of blood-brain barrier permeability in health and disease | 2019 . 01 |
4 | ,1st PAPRSB IHS Universiti Brunei Darussalam and CMU Joint Scientific Symposium,Universiti Brunei Darussalam,2019.01.16~2019.01.16,Conserved Strategy for Nociceptive Stimulation by Animal Venom | 2019 . 01 |
5 | Hypothermia but not MK801 protects against brain infarction caused by distal middle cerebral arterial occlusion,Society for Neuroscience’s 48th Annual Meeting,San Diego, USA,2018.11.03~2018.11.07, | 2018 . 11 |
6 | ,2018 2nd CMU-HYU Joint Symposium,B2, Evergreen Laurel Hotel, Taichung,2018.11.23~2018.11.23,Conserved Strategy for Nociceptive Stimulation by Animal Venom | 2018 . 11 |
7 | ,2018 CMU-UCI-MDACC Joint Symposium,Evergreen Laurel Hotel, Taichung,2018.10.20~2018.10.20,Conserved strategy for nociceptive stimulation by animal venom | 2018 . 10 |
8 | The Role of the Blood-Brain Barrier in Ischemic Stroke: Pathogenesis and Treatment Delivery,107 年度國家衛生研究院生物醫學學術研討會,國家衛生研究院,2018.08.15~2018.08.16, | 2018 . 08 |
9 | Rapid and reversible disruption of the blood-brain barrier through carbogen inhalation,The 41st Annual Meeting of the Japan Neuroscience Society,Kobe, Japan,2018.07.26~2018.07.29, | 2018 . 07 |
10 | Hypothermia protects against brain infarction caused by distal middle cerebral arterial occlusion,The 41st Annual Meeting of the Japan Neuroscience Society,Kobe Convention Center,2018.07.26~2018.07.29, | 2018 . 07 |
11 | ,2nd CMU-NUS Joint Symposium,Freshfields Hotel, Taichung,2018.05.21~2018.05.22,Conserved strategy for nociceptive stimulation by animal venom | 2018 . 05 |
12 | ,The 1st MU-CMU Symposium,Mahidol University, Thailand,2018.01.15~2018.01.15,Stroke Intervention and Pathways: NMDA Receptors and Beyond | 2018 . 01 |
13 | Isoflurane mitigates Evans blue dye extravasation caused by carbogen inhalation in mice and rats,Neuroscience 2017,Washington, DC, USA,2017.11.11~2017.11.15, | 2017 . 11 |
14 | ,中國醫藥大學-加州大學爾灣分校 聯合學術研討會,中國醫藥大學,2016.12.09~2016.12.09,The 2016 CMU-UCI Joint Symposium-介紹 John H. Weiss | 2016 . 12 |
15 | ,生物資訊與訊息傳遞研究所專題演講,國立成功大學,2016.11.04~2016.11.04,(專題研講)血腦屏障:生理變化以及藥理研究 | 2016 . 11 |
16 | Adenosine receptor agonist and the blood-brain barrier: A story to be retold,Cell Symposia: Big Questions in Neuroscience,San Diego, USA,2016.11.10~2016.11.11, | 2016 . 11 |
17 | The Role of the Blood-Brain Barrier in Ischemic Stroke: Pathogenesis and Treatment Delivery,105 年度國家衛生研究院生物醫學學術研討會,國家衛生研究院,2016.08.15~2016.08.16, | 2016 . 08 |
18 | Adenosine receptor agonist NECA increases cerebral extravasation of intravenous tracer independent of blood-brain barrier modulation,104年度暑期科學研習營暨精進學習群成果發表會,中國醫藥大學 互助大樓1A01教室,2015.09.19~2015.09.19, | 2015 . 09 |
19 | ,第六屆台灣八校臨醫所 聯合教學研究研討會,中國醫藥大學 立夫教學大樓 1樓 101教室,2015.07.18~2015.07.18,Blood-brain barrier: physiology and pharmacology | 2015 . 07 |
20 | Isoflurane attenuates cerebral ischemia-reperfusion injury induced blood brain barrier disruption,Euroanaesthesia 2015,CityCube Berlin, Germany,2015.05.30~2015.06.02, | 2015 . 05 |
21 | Inflow versus outflow ischemia: differentiation and pharmacological characterization using cellular models,Experimental Biology 2014,San Diego, USA,2014.04.26~2014.04.30, | 2014 . 04 |
22 | Double-edged effect of early reperfusion on arrhythmias and death after transient coronary artery occlusion in the rat,Experimental Biology 2014,San Diego, USA,2014.04.26~2014.04.30, | 2014 . 04 |
23 | Double-edged Effect of Early Reperfusion on Ventricular Arrhythmias and Death After Transient Coronary Artery Occlusion In The Rat,Experimental Biology 2014,San Diego convention center, CA,2014.04.26~2014.04.30, | 2014 . 04 |
24 | Measurement of Evans blue dye concentration in central and peripheral tissue following administration in vitro and in vivo: dose- and replicate- dependent effects on absorbance, fluorescence, and extraction by trichloroacetic acid,Experimental Biology 2014,San Diego, USA,2014.04.26~2014.04.30, | 2014 . 04 |
25 | Region-, dose-, and state-dependency of isoflurane-induced changes in blood-brain barrier permeability,Experimental Biology 2013,Massachusetts, USA,2013.04.20~2013.04.24, | 2013 . 04 |
26 | In vivo Evans blue dye infusion allows monitoring of auto-reperfusion in a rat model of cardiac ischemia,Experimental Biology 2013,Massachusetts, USA,2013.04.20~2013.04.24, | 2013 . 04 |
27 | In vivo Evans blue dye infusion allows monitoring of autoreperfusion in a rat model of cardiac ishemia,Experimental Biology 2013,Boston Convention Center, USA,2013.04.20~2013.04.24, | 2013 . 04 |
28 | HMW-way and LMW-way: different routes of cerebral extravasation by Evans blue and sodium fluorescein,Experimental Biology 2013,Massachusetts, USA,2013.04.20~2013.04.24, | 2013 . 04 |
29 | Vascular-dependency of Evans blue dye delivery in circulation-paired rats,Blood Brain Barrier meeting,New York, USA,2012.12.05~2012.12.08, | 2012 . 12 |
30 | Developmental loss of blood brain barrier integrity between young and adult rats,Blood Brain Barrier meeting,New York, USA,2012.12.05~2012.12.08, | 2012 . 12 |
31 | Pharmacokinetics and regional distribution of Evans blue dye in blood-brain barrier research,Blood Brain Barrier meeting,New York, USA,2012.12.05~2012.12.08, | 2012 . 12 |
32 | Stroke Intervention Pathways: NMDA receptors and Beyond,The 8th Asia Pacific Symposium on Neural Regeneration (APSNR),NTUH International Convention Center,2012.04.13~2012.04.15,Translating Discoveries to Human Therapies | 2012 . 04 |
33 | New method for protein knockdown: targeted degradation of non-tagged protein via protein-protein interaction with ubiquitin-tagged protein,Society for Neuroscience annual meeting 2011,Washington DC, USA,2011.11.12~2011.11.16, | 2011 . 11 |
專書
暫無資料研究計畫
研究計畫/Research Grant (研究類型,研究計畫代號,主持人,補助或委託單位名稱,計畫名稱,計畫期間) |
日期 | |
1 | 個別型,CMU113-MF-09,,本校(含附醫),探討鈉鈣交換蛋白在發炎性與神經性疼痛所扮演的角色,2024.8.1~2025.7.31 | 2024 . 08 |
2 | 個別型,NSTC 113-2320-B-039-015-MY3,,科技部,探討鈉鈣交換蛋白在發炎性與神經性疼痛所扮演的角色,2024.8.1~2025.7.31 | 2024 . 08 |
3 | 學生參與計畫,CMU112-SR-62,,本校(含附醫),The potential role of neural progenitor cells replenishing niche of brain microglial pool,2023.8.1~2024.2.29 | 2023 . 08 |
4 | 學生參與計畫,CMU112-SR-61,,本校(含附醫),The impact of activated microglia in the ischemic brain,2023.8.1~2024.2.29 | 2023 . 08 |
5 | 學生參與計畫,112-2813-C-039-069-B,,科技部,The potential role of neural progenitor cells replenishing niche of brain microglial pool,2023.7.1~2024.2.29 | 2023 . 07 |
6 | 學生參與計畫,112-2813-C-039-068-B,,科技部,The impact of activated microglia in the ischemic brain,2023.7.1~2024.2.29 | 2023 . 07 |
7 | 個別型,NHRI-EX112-10803NI,,國衛院,腦疾病的研究:雙核造血神經元的形成、特徵、角色,2023.1.1~2023.12.31 | 2023 . 01 |
8 | 學生參與計畫,CMU111-SR-60,,本校(含附醫),Investigating the Protection Effect from TAT Peptide on Cytarabine-Augmented Excitotoxicity,2022.8.1~2023.2.28 | 2022 . 08 |
9 | 個別型,MOST 110-2320-B-039-048-MY2,賴威達(Ted Weita Lai)、蔡崇豪(Chon-Haw Tsai),科技部,膠淋巴系統、末端血管病變、與老化相關的認知和憂鬱障礙:從基礎到臨床探討Omega-3脂肪酸的角色,2022.8.1~2023.7.31 | 2022 . 08 |
10 | 學生參與計畫,111-2813-C-039-070-B,,科技部,Investigating the Protection Effect from TAT Peptide on Cytarabine-Augmented Excitotoxicity,2022.7.1~2023.2.28 | 2022 . 07 |
11 | 個別型,AS-HLGC-110-05,,中研院,Population-wide preventative treatment of aging-associated cognitive impairment via adjustment of movie and TV shows frame and refresh rates,2022.7.1~2023.6.30 | 2022 . 07 |
12 | 個別型,NHRI-EX111-10803NI,,國衛院,腦疾病的研究:雙核造血神經元的形成、特徵、角色,2022.1.1~2022.12.31 | 2022 . 01 |
13 | 個別型,MOST 110-2320-B-039-048-MY2,賴威達(Ted Weita Lai)、蔡崇豪(Chon-Haw Tsai),科技部,膠淋巴系統、末端血管病變、與老化相關的認知和憂鬱障礙:從基礎到臨床探討Omega-3脂肪酸的角色,2021.8.1~2022.7.31 | 2021 . 08 |
14 | 學生參與計畫,CMU110-SR-19,,本校(含附醫),The potential mechanism underlying circadian effects on NMDAR antagonists against stroke,2021.8.1~2022.2.28 | 2021 . 08 |
15 | 學生參與計畫,CMU110-SR-18,,本校(含附醫),Investigating the Mechanism by which TAT Peptide Crosses the Blood-Brain Barrier,2021.8.1~2022.2.28 | 2021 . 08 |
16 | 個別型,AS-HLGC-110-05,,中研院,Population-wide preventative treatment of aging-associated cognitive impairment via adjustment of movie and TV shows frame and refresh rates,2021.7.1~2022.6.30 | 2021 . 07 |
17 | 學生參與計畫,110-2813-C-039-026-B,,科技部,Investigating the Mechanism by which TAT Peptide Crosses the Blood-Brain Barrier,2021.7.1~2022.2.28 | 2021 . 07 |
18 | 學生參與計畫,110-2813-C-039-027-B,,科技部,The potential mechanism underlying circadian effects on NMDAR antagonists against stroke,2021.7.1~2022.2.28 | 2021 . 07 |
19 | 整合型項下子計畫(主持人),NA,,教育部,新藥開發研究中心(TD-2),2021.1.1~2021.12.31 | 2021 . 01 |
20 | 個別型,NHRI-EX110-10803NI,,國衛院,腦疾病的研究:雙核造血神經元的形成、特徵、角色,2021.1.1~2021.12.31 | 2021 . 01 |
21 | 個別型,CMU109-MF-28,,本校(含附醫),利用碳合氣吸入性氣體打開血腦屏障之應用,2020.9.8~2021.7.31 | 2020 . 09 |
22 | 學生參與計畫,CMU109-SR-110,,本校(含附醫),Investigating the Influence of Reactive Astrocytes on Blood-Brain Barrier Integrity,2020.8.1~2021.2.28 | 2020 . 08 |
23 | 個別型,MOST 109-2320-B-039-066,賴威達(Ted Weita Lai)、蔡崇豪(Chon-Haw Tsai)、趙蓓敏(Pei-Min Chao),科技部,膠淋巴系統、末端血管病變、與老化相關的認知和憂鬱障礙:從基礎到臨床探討Omega-3脂肪酸的角色,2020.8.1~2021.7.31 | 2020 . 08 |
24 | 個別型,MOST 109-2320-B-039-010,,科技部,利用碳合氣吸入性氣體打開血腦屏障之應用,2020.8.1~2022.7.31 | 2020 . 08 |
25 | 學生參與計畫,109-2813-C-039-115-B,,科技部,Investigating the Influence of Reactive Astrocytes on Blood-Brain Barrier Integrity,2020.7.1~2021.2.28 | 2020 . 07 |
26 | 個別型,NHRI-EX109-10803NI,,國衛院,腦疾病的研究:雙核造血神經元的形成、特徵、角色,2020.1.1~2020.12.31 | 2020 . 01 |
27 | 學生參與計畫,CMU108-SR-100,,本校(含附醫),Investigating the contribution of neuron, astrocyte, and microglia to blood-brain barrier formation,2019.8.1~2020.2.29 | 2019 . 08 |
28 | 個別型,MOST 108-2320-B-039-016-,,科技部,大腦膠質細胞於缺血性血腦屏障破壞所扮演的角色(II),2019.8.1~2020.10.31 | 2019 . 08 |
29 | 學生參與計畫,CMU108-SR-98,,本校(含附醫),The comparison of blood-brain barrier disruption in young and aged mice following stroke.,2019.8.1~2020.2.29 | 2019 . 08 |
30 | 學生參與計畫,108-2813-C-039-125-B,,科技部,The comparison of blood-brain barrier disruption in young and aged mice following stroke.,2019.7.1~2020.2.28 | 2019 . 07 |
31 | 個別型,CMU108-Z-03,,本校(含附醫),2019合作種子計畫(2019 CMU-NUS Joint Seed Grant Funding)-Role of microbiota in the regulation of blood-brain barrier permeability during Parkinson's disease pathogenesis,2019.7.25~2020.7.31 | 2019 . 07 |
32 | 學生參與計畫,108-2813-C-039-127-B,,科技部,Investigating the contribution of neuron, astrocyte, and microglia to blood-brain barrier formation,2019.7.1~2020.2.28 | 2019 . 07 |
33 | 個別型,NHRI-EX108-10803NI,,國衛院,腦疾病的研究:雙核造血神經元的形成、特徵、角色,2019.1.1~2019.12.31 | 2019 . 01 |
34 | 個別型,MOST 107-2320-B-039-067-,,科技部,大腦膠質細胞於缺血性血腦屏障破壞所扮演的角色,2018.11.1~2019.10.31 | 2018 . 11 |
35 | 個別型,CMU107-CR-01,,本校(含附醫),根據新發現的疼痛受體,研發生物製劑的無痛配方,2018.5.1~2018.12.31 | 2018 . 05 |
36 | 個別型,NHRI-EX107-10412NC,,,血腦屏障在缺血性中風所扮演的角色:病理機制與藥物傳輸,2018.1.1~2018.12.31 | 2018 . 01 |
37 | 個別型,DMR-107-105,,附醫院內計畫,利用創新動物模型觀察造血細胞與神經細胞之結合,2017.8.1~2018.7.31 | 2017 . 08 |
38 | 學生參與計畫,CMU106-SR-67,,本校(含附醫),Modulation of blood-brain barrier permeability by adenosine receptor signaling,2017.8.1~2018.2.28 | 2017 . 08 |
39 | 個別型,MOST 106-2320-B-039-033-,,科技部,以創新動物模型研究血腦屏障通透性之生理變化,2017.8.1~2018.7.31 | 2017 . 08 |
40 | 學生參與計畫,CMU106-SR-66,,本校(含附醫),Roles of Microglia in Blood-Brain Barrier Disruption and Brain Infarction Following Stroke,2017.8.1~2018.2.28 | 2017 . 08 |
41 | 學生參與計畫,106-2813-C-039-067-B,,科技部,Modulation of blood-brain barrier permeability by adenosine receptor signaling,2017.7.1~2018.2.28 | 2017 . 07 |
42 | 學生參與計畫,106-2813-C-039-066-B,,科技部,Roles of Microglia in Blood-Brain Barrier Disruption and Brain Infarction Following Stroke,2017.7.1~2018.2.28 | 2017 . 07 |
43 | 個別型,NHRI-EX106-10412NC,,,血腦屏障在缺血性中風所扮演的角色:病理機制與藥物傳輸,2017.1.1~2017.12.31 | 2017 . 01 |
44 | 個別型,CMU105-S-14,,本校(含附醫),阿糖胞苷化療造成腦神經受損之機制:興奮性毒性所扮演的角色,2016.9.7~2017.7.31 | 2016 . 09 |
45 | 個別型,MOST 105-2320-B-039-007-,,科技部,靜脈注射由神經膠細胞所衍生的促神經生長因子以治療巴金森氏症候群,2016.8.1~2017.7.31 | 2016 . 08 |
46 | 學生參與計畫,CMU105-SR-46,,本校(含附醫),Revisiting the role of adenosine receptor signaling on blood-brain barrier permeability,2016.8.1~2017.2.28 | 2016 . 08 |
47 | 學生參與計畫,CMU105-SR-45,,本校(含附醫),NMDAR based therapeutics for neuroprotection against ischemic stroke,2016.8.1~2017.2.28 | 2016 . 08 |
48 | 學生參與計畫,105-2815-C-039-047-B,,科技部,Revisiting the role of adenosine receptor signaling on blood-brain barrier permeability,2016.7.1~2017.2.28 | 2016 . 07 |
49 | 學生參與計畫,105-2815-C-039-046-B,,科技部,NMDAR based therapeutics for neuroprotection against ischemic stroke,2016.7.1~2017.2.28 | 2016 . 07 |
50 | 個別型,NHRI-EX105-10412NC,,國衛院,血腦屏障在缺血性中風所扮演的角色:病理機制與藥物傳輸,2016.1.1~2016.12.31 | 2016 . 01 |
51 | 學生參與計畫,CMU104-SR-06,,本校(含附醫),在全腦性缺血模型下,血腦屏障的破壞和腦神經細胞損壞的關係,2015.8.1~2016.2.28 | 2015 . 08 |
52 | 整合型項下子計畫(主持人),CMU104-S-15-02,,本校(含附醫),調控NR2A and NR2B以治療神經退化疾病-以NMDA受體調節劑抑制與回復病理性突觸變化,2015.8.1~2016.7.31 | 2015 . 08 |
53 | 學生參與計畫,104-2815-C-039-006-B,,科技部,在全腦性缺血模型下,血腦屏障的破壞和腦神經細胞損壞的關係,2015.7.1~2016.2.28 | 2015 . 07 |
54 | 個別型,NHRI-EX104-10412NC,,國衛院,血腦屏障在缺血性中風所扮演的角色:病理機制與藥物傳輸,2015.1.1~2015.12.31 | 2015 . 01 |
55 | 個別型,MOST 103-2321-B-039-002,,科技部,腦缺血引發之長期抑制突觸效能 (LTD) : 從診斷到治療(3/3),2014.8.1~2015.7.31 | 2014 . 08 |
56 | 個別型,DMR-104-079,,附醫院內計畫,血中氣體對血腦屏障之影響:生理研究與藥理應用,2014.8.1~2015.7.31 | 2014 . 08 |
57 | 個別型,CMU101-N2-06,,本校(含附醫),藉由抑制固醇調節元件結合蛋白治療中風,2013.8.1~2014.5.31 | 2013 . 08 |
58 | 個別型,CMU102-NSC-S1,,本校(含附醫),多重谷氨酸次型受體導致腦中風後神經元死亡之機制-多重谷氨酸次型受體導致腦中風後神經元死亡之機制,2013.8.1~2014.7.31 | 2013 . 08 |
59 | 個別型,NSC 102-2321-B-039-008,,科技部,腦缺血引發之長期抑制突觸效能 (LTD) : 從診斷到治療(2/3),2013.8.1~2014.7.31 | 2013 . 08 |
60 | 個別型,CMU101-N2-06,,本校(含附醫),藉由抑制固醇調節元件結合蛋白治療中風,2013.6.1~2013.7.31 | 2013 . 06 |
61 | 個別型,DMR-102-125,賴威達(Ted Weita Lai)、陳坤堡(Kuen-Bao Chen),附醫院內計畫,不同壓力模式對血腦屏障的影響,2013.2.1~2013.12.31 | 2013 . 02 |
62 | 個別型,CMU101-NSC-03-2,,本校(含附醫),多重谷氨酸次型受體導致腦中風後神經元死亡之機制-多重谷氨酸次型受體導致腦中風後神經元死亡之機制,2012.8.1~2013.7.31 | 2012 . 08 |
63 | 個別型,DMR-102-100,賴威達(Ted Weita Lai)、陳坤堡(Kuen-Bao Chen),附醫院內計畫,Ketamine和isoflurane對血腦屏障的影響,2012.8.1~2013.6.30 | 2012 . 08 |
64 | 個別型,NSC 101-2321-B-039-008,,科技部,腦缺血引發之長期抑制突觸效能 (LTD) : 從診斷到治療(1/3),2012.8.1~2013.7.31 | 2012 . 08 |
65 | 個別型,DMR-101-120,,附醫院內計畫,腦缺血引發之長期抑制突觸效能 (LTD) : 從診斷到治療,2012.2.1~2012.12.31 | 2012 . 02 |
66 | 個別型,NSC 101-2320-B-039-001,,科技部,帶泛素蛋白引導目標蛋白之降解,2012.1.1~2012.10.31 | 2012 . 01 |